Finally, we only investigated three SNPs of IFN-lambda3 (rs8099917, 11881222, and 8103142) because we did not have the ability to analyze other SNPs, but examining other SNPs of IFN-lambda3 (as well as IFN-lambda1, IFN-lambda2, IL-10R beta, and IL-28R alpha) in the future could increase understanding of the role of IFN-lambdas and their receptors in RCC. The gene discussed is IFNL1; the disease is renal cell carcinoma.