Although the overall pattern of increased induction of the distinct families was similar between the tumor milieu and draining lymph nodes, statistical significance was not achieved in several transcripts in the tumor (GzmB, IL7R, TNF, PRF1) and likely reflects the CD3+ T cell sort in the lymph node versus the total CD45+ hematopoietic sort in the tumor. The gene discussed is PRF1; the disease is neoplasm.