To investigate the mechanism of miR-27b in colorectal cancer, we screened the target genes of miR-27b by using TargetScan (http://www.targetscan.org/), miRDB (http://www.mirdb.org/miRDB/) and picTar (http://pictar.mdc-berlin.de/), and found that Rab3D was identified as a candidate (Figure 4A). The gene discussed is RAB3D; the disease is colorectal cancer.