To summarise our miRNA studies to date, laminin-332-ITGA6/ITGB4 and laminin-332-ITGA3/B1 pathways were regulated by antitumor miRNAs, i.e., the miR-29 family, miR-218, miR-150-5p/-3p, and the miR-199 family, in HNSCC cells (Figure 7). The gene discussed is ITGB4; the disease is head and neck squamous cell carcinoma.