PLOD1 and hypogonadism: In particular, at 2 years of follow-up the prevalence of patients showing subclinical hypogonadism (T ≥ 10.4 nmol/L and LH ≥ 8 IU/L [12]) was significantly higher in RT patients compared to SURV (respectively 59/131 vs 13/61; P < 0.001).