Moreover, there was a significant correlation between SLC7A5 expression by peripheral monocytes and the IL-1β mRNA level in RA patients, suggesting that SLC7A5-mediated metabolic reprogramming may contribute to establishment of the inflammatory milieu in RA disease (Figure 6B, R2 = 0.3935, p = 0.0014). The gene discussed is SLC7A5; the disease is rheumatoid arthritis.