The concurrent expression of cell adhesion molecules and oncogenes with CG is shared between AML and ALL cells and has been ascribed to CG-mediated modulation and cleavage; in addition to the phosphorylation of oncogenes, such as SRC, YAP1, and FOXO3, in ALL, this supports their role in the association between CG expression and worse prognosis. Here, FOXO3 is linked to acute myeloid leukemia.