HNF1B and familial pancreatic carcinoma: In a combined meta-analysis of up to 11,537 pancreatic cancer cases and 17,107 control individuals from PanScan I+II, PanScan III, PanC4, and PANDoRA, we identified three additional loci of genome-wide significance: rs13303010 at 1p36.33 (NOC2L, odds ratio (OR) = 1.26; 95% confidence interval (CI) 1.19–1.35, P = 8.36 × 10−14: Wald test), rs2941471 at 8q21.11 (HNF4G, OR = 0.89, 95% CI 0.85–0.93, P = 6.60 × 10−10: Wald test), and rs4795218 at 17q12 (HNF1B, OR = 0.88, 95% CI 0.84–0.92, P = 1.32 × 10−8: Wald test).