Characterization of myeloid subpopulations in the colon LP of untreated C57BL/6J mice and in “spontaneously” formed tumours obtained from 5-month-old ApcMin/+ mice confirmed the presence of all myeloid subpopulations described in Fig. 1, although with a clear increase in the proportion of the tumoural CD11b+F4/80− neutrophil fraction (up to 70% of total CD11b+ cells) (Supplementary Fig. 1). The gene discussed is ITGAM; the disease is neoplasm.