CRP and coronary artery disorder: Besides severity of coronary obstruction [37, 38], numerous factors that could possibly attenuate the development and biological function of coronary collaterals have been reported such as old age [39], traditional risk factors for coronary artery disease [40–44], hyperlipoprotein (a) [45], hyperuricemia [46] and elevated serum levels of CRP [47], TNF-a [48], N-terminal pro-brain natriuretic peptide [38] and mimecan [49], and high neutrophil/lymphocyte ratio [50].