Because PcG protein BMI1 may regulate AKT and ERK pathways [32], we analyzed the expression of total AKT, phospho-AKT(p-AKT), total ERK and phospho-ERK (p-ERK) in control, CBX7-overexpressing (CBX7-oe), and CBX7-shRNA (CBX7i) gastric cancer cell lines. Here, AKT1 is linked to gastric cancer.