TP53 and cancer: Inducible porcine models have also been generated using the latent oncogenic mutations KRASG12D (Li et al., 2015; Schook et al., 2015) and TP53R167H (Leuchs et al., 2012; Schook et al., 2015), a mutation that is orthologous to the human R175H TP53 mutation; both of these represent mutations commonly found in human cancer (Levine and Oren, 2009; Pylayeva-Gupta et al., 2011).