GPT and cholestasis: Liver function tests are a useful diagnostic tool; thus, an elevation in AST and the liver‐specific ALT indicates leakage from injured tissues caused by hepatocellular necrosis,23 while increase in ALP level is due to overproduction and release in blood following hepatobiliary injury and cholestasis.24 In this study, significant increases in serum AST, ALT, and ALP levels compared with control were observed after administration of doxorubicin and 5‐FU.