To determine the clinicopathological relevance of TLSs in intestinal‐type human GC, we investigated the expression of a 3‐gene TLS signature comprising the homeostatic chemokines CXCL13, CCL19 and CCL21 (identified in the gp130F/F mouse model; see Fig. 3) in TCGA data sets (Figs. 6b–6d). Here, CXCL13 is linked to gastric cancer.