STAT3 and Autoimmunity: Many of the above STAT3‐activating cytokines are linked with the development, maintenance or effector function of Th17 cells.44 This T cell subset, and its signature cytokine IL‐17, has been associated with TLS development in infection, autoimmunity, allograft rejection and cancer.4, 35, 39, 40, 41 Nevertheless, a role for Th17/IL‐17 in TLS development remains controversial and is likely disease‐ and context‐dependent.