MAP3K5 and gastric carcinoma: Ginsenoside F2 also induced the apoptosis through accumulation of ROS production followed by a decrease in MTP, Cyt C release, and modulation of apoptosis signal-regulated kinase-1 (ASK-1)/JNK signaling cascade, which triggered the caspase-dependent apoptotic pathway in humor gastric carcinoma SGC7901 cells (Figure 3).