EIF4EBP1 and cancer: There was no significant correlation between underexpression of nuclear p-4EBP1 and long-term prognosis among cancer patients (3-year overall survival: P = 0.27; 5-year overall survival: P = 0.25), although a significant correlation exists between overexpression of total p-4EBP1 and 3-year (P < 0.00001) and 5-year (P < 0.0001) overall survival (Supplementary Figures 15 and 16).