Also, p-4EBP1 Thr37/46 instead of p-4EBP1 Thr70, and total p-4EBP1 but not cytoplasmic or nuclear-positive p-4EBP1, act as prognostic predictors in most cancers, which provide more precise data to guide the clinical evaluations for diagnosis and prognosis. The gene discussed is EIF4EBP1; the disease is cancer.