We performed subgroup analysis and the results revealed that patients with high GLUT-1 expression were more likely to have poor OS in gastric cancer, urinary carcinoma, ovarian carcinoma, oral squamous cell carcinoma, pancreatic adenocarcinoma, colorectal cancer, lung cancer, gallbladder carcinoma, esophageal squamous cell carcinoma. The gene discussed is SLC2A1; the disease is pancreatic adenocarcinoma.