We performed subgroup analysis and the results revealed that patients with high GLUT-1 expression were more likely to have poor OS in gastric cancer, urinary carcinoma, ovarian carcinoma, oral squamous cell carcinoma, pancreatic adenocarcinoma, colorectal cancer, lung cancer, gallbladder carcinoma, esophageal squamous cell carcinoma. This evidence concerns the gene SLC2A1 and colorectal cancer.