Furthermore, since (i) CXCR3 staining was mainly observed in epithelial cells within the tumor, (ii) the protein levels for CXCR3A were significantly higher in TPC-1 than in Nthy-ori-3-1 and (iii) CXCR3B protein levels in TPC-1 were significantly lower than CXCR3A and (iv) CXCR3B levels in TPC-1 were lower than Nthy-ori-3-1), we propose that increased CXCR3 levels found in PTC by immunohistochemistry analysis correspond to the CXCR3A variant mainly expressed in PTC epithelial cells with a minor CXCR3A expression from inflammatory cells [74, 78, 79]. Here, CXCR3 is linked to neoplasm.