When comparing CXCR3 ligands expression in nMPTC with or without thyroid inflammation respect to B-CLT, a significant increase of all ligands only in nMPTC with thyroiditis (CXCL4: 3.236±3.855, p=0.469; CXCL9: 5.021±4.166, p=0.0039; CXCL10: 2.713±1.574, p=0.0039; CXCL11: 8.121±10.21, p=0.0098) was observed (Figure 2G). The gene discussed is CXCR3; the disease is thyroid gland disorder.