On the other hand, however, Chikova et al. appear to take a different view that CHRNA3 SNP rs8040868 as well as CHRNA9 SNP rs56159866 and rs6819385 give rise to a higher risk of non-small cell lung cancer, while the effect of CHRNA9 SNP rs55998310, rs56291234 and rs410759555 are exactly the opposite. The gene discussed is CHRNA3; the disease is non-small cell lung carcinoma.