TP53 and neuroblastoma: Our analyses confirmed published reports, and showed that SK-N-SH, SH-SY5Y, IMR32, IMR5 and LAN5 cell lines harbor wildtype TP53, while the Kelly cell line harbors a 529C>T (P177T) missense mutation in TP53. Relative MDM2 expression was higher in the five neuroblastoma cell lines lacking TP53 mutations than in Kelly cells (Figure 2B).