To further investigate potential molecular mechanisms of MALAT1 for promoting metastasis of triple negative and Her-2 positive breast cancers, the expressions of XBP1 and HIF-1α in samples with non-metastatic TNBC, highly metastatic TNBC, non-metastatic Her-2 positive and highly metastatic Her-2 positive breast cancer were detected by qRT-PCR. This evidence concerns the gene ERBB2 and breast carcinoma.