In addition, there were multiple genes induced that are involved with cell and organelle structure and function (PNCK, UBD, CDH2, HERC5) and importantly, genes associated with the prostate, AR (MMP7, CDH2, ENO2, IGFBP3) and cancer (IFIT3, IFI44L). The gene discussed is IGFBP3; the disease is cancer.