The results showed that SNHG1 was positively correlated with target genes of miR-145 in colorectal cancers (SNHG1 and p70S6k: r: 0.353, p= 3.57E -11; E2F3: r: 0.582, p= 1.86E -31; Figure 4E). The gene discussed is SNHG1; the disease is colorectal cancer.