Decreased Cav-1 staining in stromal fibroblasts was significantly associated with decreased overall survival both as a trend (Log-rank test for trend p=0.0153) or when comparing low (0-1 score) to high (2-3 score) (Log-rank test p=0.0222) in NSCLC. The gene discussed is CAV1; the disease is non-small cell lung carcinoma.