The strongest trends were observed by examining the tumour nest to stromal ratios (TN/STR) where those with higher TN/STR ratios of CD8, CD68 or FoxP3 had higher overall survival (Figure 1F-1H); however, this only reached significance for CD8+ T cells (p=0.041 Mantel-Cox Log-rank test, p=0.0294 Gehan-Breslow Wilcoxon test). The gene discussed is FOXP3; the disease is neoplasm.