Results of multivariate analysis for our investigational markers are shown in Table 1, where it can be seen that CD8 numbers (total, tumour nest or stromal number) was a significant predictor of survival with small hazard ratios; however, high CD8 TN/STR ratio was a significant predictor of better overall survival (p=0.037) with hazard ratio of 0.645 (95%CI 0.427-0.974). Here, CD8A is linked to neoplasm.