ABCG2 and Hermansky-Pudlak syndrome: The resistance mechanism of HPS to tildipirosin or other macrolides may be associated with the pathways of amino acid ATP-binding cassette (ABC) transporter system (HAPS_2069, HAPS_RS03630) and the metabolite transporter superfamily (HAPS_2067 and HAPS_2068, HAPS_RS08950) [49, 50, 55, 56], which will be a focus of future studies.