In agreement with previous reports [34, 35], two EGFR-activated cell lines, NCI-H3255 (L858R) and PC-9 (del19), were highly sensitive to the first-generation EGFR inhibitors, gefitinib and erlotinib (Figure 2B and 2C), when compared with five other NSCLC cell lines carrying wild type EGFR. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.