CCL8 and graft versus host disease: The group of Yamamoto et al [64] also correlate the early expression of plasmatic CC-chemokine ligand motif 8 (CCL8) to GVHD and taken together with an involvement of allo-recognition in CCL8 expression, it suggests that CCL8 plays an important role in GVHD pathology, but more detailed analysis and further experiments are required to draw a clear conclusion.