Meanwhile, by interacting with miRNAs, circRNAs also have the potential of impacting a variety of signaling pathways in cancers, such as vascular endothelial growth factor A (VEGFA) signaling pathway [91], large tumor suppressor kinase 1 (LATS1) [121], Src family tyrosine kinases (SFKs) [122] and so on. This evidence concerns the gene LATS1 and cancer.