Yu’s group executed qPCR analysis of circRNAs in 66 HCC tissues and reported a carcinogenic circRNA, ciRS-7, which promotes HCC cell proliferation by targeting miR-7 and elevating the expression of the direct target gene PIK3CD (phosphatidylinositol 3-kinase catalytic subunit delta) [60]. Here, PIK3CD is linked to hepatocellular carcinoma.