IGF2 and H19 were imprinted in all the normal squamous epithelium of 49 HNSCC samples examined (77% of 64 samples), while 12 of 32 samples(37.5%) confirmed LOI at the H19 gene and 11 of 27 samples (40.7%) proved LOI at the IGF2 gene [49]. Here, H19 is linked to head and neck squamous cell carcinoma.