Recently, a class of long intergenic noncoding RNAs named papillary thyroid cancer susceptibility candidate (PTCSC), such as PTCSC1 (located in 8q24), PTCSC2 (located in 9q22) and PTCSC3 (located in 14q13), might predispose infected persons to thyroid cancer. The gene discussed is PTCSC3; the disease is thyroid cancer.