For example, Tan et al. demonstrated that double-negative feedback loop between long non-coding RNA TUG1 and miR-145 promotes epithelial to mesenchymal transition and radioresistance in human bladder cancer cells [36]; and Ji et al. long non-coding RNA TUG1 on gastric cancer cell transference and invasion through regulating and controlling the expression of miR-144/c-Met axis [37]. The gene discussed is MET; the disease is urinary bladder cancer.