Moreover, increased levels of positive acute phase proteins like C-reactive protein (CRP), haptoglobin, galectin-3, IL6, G-CSF, sICAM-1, high neutrophil-to-lymphocyte ratio (NLR) and decreased levels of negative acute phase proteins like albumin, pre-albumin, and transferrin have been found in sera of patients with thyroid cancers [5–8]. The gene discussed is CRP; the disease is thyroid cancer.