VEGFC and metastatic malignant neoplasm in the lymph nodes: In addition, even though some studies have detected that overexpression of vascular endothelial growth factor C (VEGF-C) mRNA in thyroid cancer tissue has been associated with a high prevalence of lymph node metastasis, any such association could not be studied in the current AMORIS study due to lack of information on VEGF-C [31–35].