ZEB2 expression was significantly correlated with Sp1 expression in human colorectal cancers (n = 244, r = 0.200, P = 0.00166 and n = 382, r = 0.166, P = 0.00113 for TCGA, Nature 2012, and TCGA, Provisional, studies, respectively) (Figure 7A). This evidence concerns the gene SP1 and colorectal cancer.