ANO1 and gastrointestinal stromal tumor: Supportively, the expression of ANO1 was not restricted to the interstitial cells of Cajal or gastrointestinal stromal tumors and was widely expressed in normal tissues, such as smooth muscle and epithelial cells [6], and various human tumors, such as renal oncocytoma, chromophobe renal cell carcinoma, pancreatic neoplasms, salivary gland neoplasms, synovial sarcoma, leiomyoma, pancreatic adenocarcinoma, and leiomyosarcoma [7].