We then tested the expression levels of HBXIP (Figure 7A) and PPARδ (Figure 7B) of 83 cases of colonic paraffin-embedded specimen and 12 cases of normal colonic tissues by immunohistochemical assays (Supplementary Table 3), the results demonstrated that Both HBXIP and PPARδ were highly expressed in the colonic tumor tissues and showed a positive correlation between HBXIP and PPARδ expression in the carcinoma tissues, which suggests that HBXIP had played important roles in the progression of colonic carcinoma cells. The gene discussed is PPARD; the disease is colon carcinoma.