TLR4 and cervical cancer: In cervical cancer, the reported changes in expression of TLR4 are a source of controversy and effects seen may be related to the HPV type and different material and methods used; the cervical carcinoma lines SiHa (HPV16+) show higher expression of TLR4 than HeLa (HPV18+), moreover SiHa, but not HeLa display resistance to apoptosis following treatment with LPS, via TLR4 [21].