SQSTM1 and adult-onset Still disease: Although statistical significance was not reached, chloroquine treatment enhanced p62 protein expression of in PBMCs from AOSD patients (1.1 ± 0.8 vs. 1.3 ± 0.3) and HCs (0.5 ± 0.1 vs. 1.0 ± 0.3) (Figure 4E).