CIAO3 and tetanus: We found significantly lower IFN-γ levels in aP-primed compared with wP-primed children for FHA before the booster, for all four antigens (PT, FHA, Prn, and tetanus) at 1 month and for PT, FHA, and tetanus 1 year post-booster (Figure E2 in Supplementary Material), while IL-13 levels only differed for Prn before the booster vaccination between wP- and aP-primed children.