LANCL1 and Familial prostate cancer: Next, we assessed the level of LanCL1 protein in various prostate cancer cell lines and found that LanCL1 was highly expressed in the PC-3 and DU145 metastatic prostate cancer cells, but we detect a relatively much lower LanCL1 expression in the benign or weakly metastatic prostate cancer cells including BPH-1 and LNCaP (Fig. 2c, d).