EGFR and neoplasm: In particular, T cells precisely and efficiently expressed EGFR-CAR lysed EGFR+ NSCLC H23 and H460 cells but not EGFR-negative gastric cancer HGC27 cell line (Fig. 3a and Figure S2B, C), indicating that these re-engineered T cells acquired specific cytolytic activity against EGFR+ tumor cells.