Given the elevated expression of miR-124 in HCC tissues, we explored miR-124 expression in HCC cell lines (Huh7, MHCC-LM3, HepG2, SMMC-7721, and PLC) and the hepatocyte cell line HL-7702 (L02) and found that miR-124 was downregulated in HCC cells (Fig. 1b). Here, HSPG2 is linked to hepatocellular carcinoma.