Second, some potentially useful information was unavailable because medical records and laboratory test results of each patient were not included in the claim data; detailed characteristics of anterior uveitis (e.g., grade of inflammation, granulomatous or nongranulomatous), details of AS manifestation at onset, human leukocyte antigen B27 positivity, and levels of C-reactive protein and acute-phase reactant at the onset of uveitis or AS were not considered. The gene discussed is CRP; the disease is anterior uveitis.