VEGFA and neoplasm: In addition to well described antioxidative and pro-apoptotic functions, tocotrienols have demonstrated other interesting properties as possible treatments for cancer, including the induction of antitumor immunity, the inhibition of epithelial-to-mesenchymal transitions, the suppression of vascular endothelial growth factor tumor angiogenic pathway and more recently, chemosensitization and anti-cancer stem cell effects [20].