Examination of the prognostic significance of INPP4B in the Verhaak, TCGA and OCI/PM AML datasets with CoxPH SubID identifies optimal cut-offs for INPP4B at 87% in the Verhaak dataset (P = 1.02E-06, median cut-off P = 9.77E-04), 76% in the TCGA dataset (P = 0.0224, median cut-off P = 0.359), and 75% in the OCI/PM dataset (P = 6.48E-06, median cut-off P = 0.0373) (Fig 2A, 2E and 2I). The gene discussed is INPP4B; the disease is acute myeloid leukemia.