In our NSCLC patient cohort, we have investigated associations between CAF subtypes and lymphoid cells including T-cells (CD3+), CD4+ T-helper cells, CD8+ cytotoxic lymphocytes, memory T-cells (CD45RO), T-regulatory cells (FoxP3+), B-lymphocytes (CD20+) and NK cells (CD56+). This evidence concerns the gene CD4 and non-small cell lung carcinoma.