Interestingly, of the 16 recurrent in-frame fusion genes, 13 (MRPL48-DTX4, THSD4-LRRC49, ASCC1-MICU1, QKI-PACRG, AFAP1-ABLIM2, SBNO2-C19orf20, MVP-KIF22, GIGYF2-EFHD1, ARFGEF1-CPA6, EFHD1-EIF4E2, SLC39A11-SDK2, BPTF-PITPNC1, and TBC1D4-COMMD6) had occurred only in breast cancer samples, but not in other cancer types. The gene discussed is EFHD1; the disease is breast carcinoma.