LGALS3 and ischemic stroke: Meanwhile, a study involving 8444 participants from the general population-based FINRISK 1997 cohort demonstrated that galectin-3 was weakly associated with incident ischemic stroke over a 15-year follow up period, but this relationship was attenuated in multivariate adjusted models, though galectin-3 levels were predictive for future cardiovascular events, such as all-cause mortality, cardiac death and heart failure [75].