A recently longitudinal study [50] showed ARID5B (transcription coactivator for histone H3K9me2 demethylation) CpG methylation is inversely associated with both ARID5B expression and atherosclerosis in human CD14+ blood monocyte, while the associations vanished in T cell samples from the same subset. The gene discussed is ARID5B; the disease is atherosclerosis.