Based on the identified salmonella infection-, NOD-like receptor-, Toll-like receptor, and MAPK-AP1 pathways, TLR1B, MYD88, NOD1, AP-1, which had the important role in regulation the immune action (Buchholz and Stephens, 2008; Ramasamy et al., 2012; Limoge et al., 2017; Wang et al., 2017), were significantly up-regulated in REV infected cells compared with control cells by RNA-sequencing and Q-PCR. This evidence concerns the gene MYD88 and Salmonella Infections.