SOD1 and amyotrophic lateral sclerosis: This is supported by the presence of oxidative stress in non-SOD1 ALS (Duan et al., 2010; Braun et al., 2011; Iguchi et al., 2012; Kiskinis et al., 2014; Carri et al., 2015; Hirano et al., 2015; Zhan et al., 2015).