Moreover, qRT-PCR studies confirmed the overexpression of the genes coding the three proteins, 40 min after induction with MMC: i) the SAM-dependent methyltransferases or AdoMet-MTases (ORF27 from Ab 105-2φ), which have been associated with protection of the viral genome of the host restriction enzymes from the bacteria21,22; and ii) MazG (ORF06), which is a pyrophosphohydrolase enzyme located in bacteriophages that infect Burkholderia cenocepacia and in marine bacteriophages (especially cyanophages), thus facilitating viral infection in the environment23. Here, THUMPD2 is linked to viral infectious disease.